How Motivation to Reduce Uncertainty Predicts COVID-19 Behavioral Responses: Strategic Health Communication Insights for Managing an Ongoing Pandemic

During highly uncertain times such as the coronavirus disease 2019 (COVID-19) pandemic, it is vital to understand and predict individuals' responses to governments' crisis and risk communication. This study draws on the Orientation-Stimulus-Orientation-Response (O-S-O-R) model to examine (1) whether uncertainty reduction motivation (a pre-orientation factor) drove Americans to turn to traditional news media and/or social media (stimuli) to obtain COVID-19 information;(2) if these media preferences shaped their COVID-19 knowledge, cognitive information vetting, and trust in government communication (post-orientation factors);and finally (3) whether these factors contributed to their intended and actual behaviors (responses), such as getting vaccinated. Thus, this study explores how multiple communicative and cognitive mechanisms contribute to public compliance with government health recommendations during a pandemic. Mediation analyses showed positive indirect effects between uncertainty reduction motivation and behavioral outcomes via use of social media (in relation to traditional news media) and COVID-19 knowledge and cognitive information vetting. This study discusses theoretical and practical health communication implications of these findings. © 2023 SAGE Publications.

[SARS CoV-2 related disease features in a population of chronic hemodialysis patients]

Patients on chronic dialysis have an increased risk for SARS CoV-2 virus disease and its complications because of multiple comorbidities and alterations in the immune response caused by renal disease. In this retrospective observational study we describe the clinical features and the evolution of SARS CoV-2-related disease in 19 patients of our Pesaro and Fano facilities, where incidence and mortality of the epidemic were among the highest in Italy. A total of 176 patients were undergoing chronic treatment, 153 hemodialysis and 23 peritoneal dialysis. The incidence of infection was 10,8%, with 84% needing hospitalization and mortality amounting to 53%. The most frequent onset symptom was fever (84,2%) and the most used therapy was an association of low molecular weight heparin and hydroxychloroquine (57,9%). Comparing the deceased and survivor populations we noticed significant differences in age and presence of cardiopathy for what concerns anamnestic data and in fatigue and dyspnea in terms of clinical presentation. LDH and CPK resulted highest among deceased patients, while the use of enoxaparin was more frequent in survivors. By observing contagions over time, we also noticed that most of the cases, and the ones with worse clinical condition and outcome, all occurred in the early stage of the epidemic and in particular within the first 20 days from the implementation and codification of the measures to prevent its spread, the only modifiable factor that had an unmistakable effect on the evolution of events.